By Mark Gladwin
(Currently in 2004 revised printing) a quick, transparent, thorough, and hugely relaxing method of scientific microbiology, brimming with mnemonics, humor, precis charts and illustrations, from AIDS to "flesh-eating micro organism" to ebola, mad cow illness, hantavirus, anthrax, smallpox, botulism, and so on. first-class Board assessment.
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Extra resources for Clinical Microbiology Made Ridiculously Simple, Edition 3
The way we treat this common and dangerous critter. Fig. 4-11. NEWS FLASH!!!! Read all about it! Streptococcus pneumoniae now resistant to penicillins! 0 micrograms/ml blood). In some European countries 2/3 of strains have intermediate or high level resistance! S. about 10% of strains have intermediate resistance and 1% high level resis- Summary of streptococcal groups. References Davies HD, McGreer, A, et al. Invasive group A streptococcal infections in Ontario, Canada. N. Eng. J. Med. 1996; 335: 547-54.
STAPHYLOCOCCI Staphylococci are forever underfoot, crawling all over hospitals and living in the nasopharynx and skin of up to 50% of people. While at times they cause no symptoms, they can become mean and nasty. They will be one of your future enemies, so know them well. The 3 major pathogenic species are Staphylococcus aureus, Staphylococcus epidermidis, and Staphylococcus saprophyticus. It is extremely important to know how to differentiate staphylococci from streptococci because most staphylococci are penicillin G resistant!
A day later the skin color changes from red to Other enzymes include streptokinase (activates 4) the proteolytic enzyme plasmin, which breaks up fibrin purple to blue, and large blisters (bullae) form. Later blood clots), hyaluronidase, DNAases, anti-C5a pepti- the skin dies and muscle may also become infected (myositis). dase, and others (see Fig. 2-S). This infection must be recognized early and the fasStaphylococcus aureus has many enzymes that are similar to those of streptococci. You will learn about these in cia surgically removed.