Download Advances in Pharmacology, Vol. 39 by J. Thomas August, M. W. Anders, Ferid Murad, Joseph T. Coyle PDF

By J. Thomas August, M. W. Anders, Ferid Murad, Joseph T. Coyle

Every one quantity of Advances in Pharmacology offers a wealthy selection of experiences on well timed themes. Emphasis is put on the molecular bases of drug motion, either utilized and experimental.

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Cerise, E. , and Loughry, R. W. Sulindac for polyposis of the colon. Am. 1. Surg. 157, 175-178. Williams, C. , Lamps, L. , Nanney, L. , Beauchamp, R. , and DuBois, R. N. (1996). Elevated cyclooxygenase-2 levels in Min mouse adenomas. Gastroenterology 111, 1134-1140. , Gumbinger, H. , and Bunte, H. The NSAID sulindac reverses rectal adenomas in colectomized patients with familial adenomatous polyposis: Clinical results of a dose-finding study on rectal sulindac administration. Int. J. Colorectal Dis.

4A). , Arg-Lys-Arg-Arg) cleavage sites in the protein. , 1994). Detailed biochemical analysis of the MMTV Sag has been hampered by its low abundance in cells. The sag genes of the various M t u loci are very homologous at both the nucleotide and the amino acid level except for their 30 C-terminal amino acids (Fig. 4B), which have been called the hypervariable domain. , 1993). Indeed, the different M t u and MMTV Sag proteins can be grouped together by the sequences of their hypervariable domain; Sag proteins that fall into the same group generally interact with the same VP-bearing T cells (Fig.

Gastroenterology 107, 1183-1 188. Fearon, E. R. ( I 994). Molecular genetic studies of the adenoma-carcinoma sequence. Adv. Intern. Med. 39, 123-147. Fearon, E. , and Vogelstein, B. (1990). A genetic model for colorectal tumorigenesis. ) 61, 759-767. Friend, W. G. (1990). Sulindac suppression of colorectal polyps in Gardner’s syndrome. Am. Fam. Physician 41, 891-894. Gann, P. , Manson, J. , Glynn, R. , Buring, J. , and Hennekens, C. H. (1993). Lowdose aspirin and incidence of colorectal tumors in a randomized trial [see comments].

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