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By Howard W. Jones Jr., Georgeanna S. Jones, Suheil J. Muasher, Debbie Jones (auth.), Shlomo Mashiach M.D., Zion Ben-Rafael M.D., Neri Laufer M.D., Joseph G. Schenker M.D. (eds.)

The international Congress of In Vitro Fertilization and exchange Assisted copy, held in Jerusalem, Israel, 2-7 April, 1989, was once the 6th within the series of those Congresses, yet used to be the 1st to stress the most important significance and where of assisted reproductive applied sciences within the remedy of infertility. The everlasting urban of Jerusalem witnessed the collection of greater than 1500 individuals from allover the realm who shared and exchanged wisdom and updated adventure during this ever-evolving box. The top of the range medical contributions to the Congress culminated within the e-book of this lawsuits. It embraces all-important elements within the box of in vitro fertilization and exchange assisted copy. Papers on controversies and diversities of tips on how to stimulate the ovaries, imaging suggestions, easy examine and cutting-edge papers on ovarian body structure, the function of GnRH and its analog, scientific elements of IVF therapy and cryopreservation, up to date thoughts in assisted reproductive applied sciences which are speedy constructing at the side of IVF, have been integrated. whilst should still IVF be most efficient to surgical procedure? What are the ex­ pected up to date global effects and what are the mental, ethical, moral and non secular implications? those are all of the matters of the treating workforce and are addressed right here. Male issue infertility is still a challenging challenge, yet advances within the knowing of sperm-egg interplay, sperm evaluate and education are suggested. Micromanipulation emerges as a potential replacement to carry a few aid to this challenge, however it additionally supplies to be principal in selling the sector of prenatal genetic analysis.

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There is no doubt that the combined pituitary suppression/ovarian stimulation therapy is not easier to apply or to monitor than the treatment with gonadotropins alone. Fertilization/ailure: Fertilization rate is primarily dependent on the quality of the male and female gametes. In IVF programs the laboratory standards and knowhow may also influence the results. e. increases the pregnancy rate. Combined Pituitary Suppression Stimulation 33 Table 1. 1 (5-20) (5-39) (1-3) (3-9) (3-7) When discussing the results of combined hypophyseal suppression/ovarian stimulation therapy one should, however, clearly distinguish between the effects due directly to each of the two components.

Cysts are formed regardless of whether GnRH-a is given during the follicular or luteal phase. Our experience indicated that ovarian stimulation in the presence of ovarian cysts can adversely affect follicular growth and outcome of IVF, while expectant management until the cysts regress spontaneously often results in prolongation of treatment for another two to three weeks, which requires the addition of a daily injection of GnRH-a Limitations in the Use ofGnRH-alhMG 19 Table 1. Number. Size and Hormonal Levels of Follicular and Luteal Cysts.

Phase I. F ertil. , 39:167 (1983). 24. J. Dor, A. Ellenbogen, Z. Ben-Raphael, S. Lipitz, D. Lev-Ran, A. Davidson, L. Nebel, D. M. Serr, E. Rudak and S. Mashiah, D-TRP6-GnRH analog for the IVF program, Proc. Israeli Congress of Fertil. Steril. Abstr. 5 (1988). 25. H. Peters and E. Levy, Cell dynamics of the ovarian cycle, J. Reprod. , 11:227 (1966). 26. A. Gougeon, Origin and growth of the preovulatory follicle(s) in spontaneous and stimulated cycles, in: Human In Vitro Fertilization; Inserm Symposium No.

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